IPODD - IBD: proteases offers new targets for drug discovery

About IPODD

The inflammatory bowel diseases (IBD) are chronic relapsing and remitting inflammatory disorders of the gastrointestinal tract.

Despite current treatment's efficacy, many patients require surgery for refractory disease or complications.

We aim to delineate the role of intestinal proteases (host-derived and bacterial) and their inhibitors in the pathophysiology of IBD.

See also the Public summary "Targeting the Demolition Squad"